This is a dubious procedure, because Arnold must first be implanted with a fertilized human egg - unusual for a woman, unheard of for a man. It's a good thing Arbogast is a persuasive talker; DeVito plays him with a conspiratorial charm, talking about the "beauty of the plan" as if it's something anyone would be lucky to participate in. The two doctors borrow an egg, Arnold donates the sperm, they inject the result into his body, and Arnold starts taking daily doses of their miracle drug.
The experiment is not only a success, but Schwarzenegger actually becomes pregnant. The movie wisely never even attempts to explain how this is possible in a person without a womb; hard science is not the strong point here. The movie's comedy, and some other scenes that are sort of touching, all come out of the man's experience as he begins to feel motherly toward his unborn child.
I know this sounds odd, but Schwarzenegger is perfect for the role. Observe his acting carefully in "Junior," and you'll see skills that many "serious" actors could only envy. He never reaches for an effect. He never grabs for a joke. He never wrings an emotion out of reluctant material. He plays the role absolutely straight, trusting the material to make the points and get the laughs. This is probably the only way this story could have worked, but not every actor would have known that.
Schwarzenegger is helped mightily by being flanked by three superb comic actors: DeVito, whose crazy enthusiasm makes the scheme almost halfway convincing; Emma Thompson, as the scientist who takes over Schwarzenegger's old lab and makes an unexpected contribution to the experiment, and Pamela Reed, as DeVito's exwife, who is pregnant herself, possibly by a member of Aerosmith.
DeVito and Thompson turn their scenes into a seminar for the study and exercise of the double take; the way they react to developments is funnier than the developments themselves. One of Thompson's gifts, which is precious here, is a way of cheerfully making the best of obviously catastrophic situations.
The movie's plot is more or less preordained by the progress of a pregnancy. We follow Arnold through morning sickness, cramps, visits to the ultrasound lab and natural childbirth classes, all given a spin by the need to keep his condition as secret as possible.
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